Margherita College was established in the year 1978 and is located on a sprawling pollution free campus of 26 bighas of land in the North Eastern state of Assam guarded by the majestic Patkai Hills in the Head quarter of Margherita Sub-Division. Margherita lies exactly 567 kms. east of Guwahati. The Patkai hills which form a gateway of India in the North-East are situated in the South-Eastern corner of Assam between 26.300 North latitude and 95.150 East longitude making the natural boundary between Assam and Myanmar. Margherita, the township near Ledo from where the historic Stilwell road connects the North-East region of India with China via Myanmar is the centre of what could be a rich economic zone of South-East Asia.